1
Define Your Structure
Set up targets and candidate molecules in the browser or through the API.
In Silico Screening Made Easy
Use state-of-the-art structure prediction tools without specialized hardware.
Built by scientists for scientists.
How Volt Works
Move from screen to insights in a few clear steps.
2
Submit Your Run
Launch large batches with managed compute and track progress in real time.
3
Analyze Results
Find top candidates and review interactive structures with confidence metrics.
In-Silico Screening Examples
DeepMind's release of AlphaFold 2 was a watershed moment for structure prediction. Since its release in 2021, AlphaFold and related algorithms have become widely adopted for hypothesis generation and discovery. See a few selected examples below.
In silico protein interaction screening uncovers DONSON's role in replication initiation
Science (2023). AlphaFold-based protein-protein interaction screening uncovered DONSON as a key replication-initiation factor.
AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
Science Advances (2024). AlphaFold-guided virtual screening identified potent TAAR1 agonists with improved hit rates.
A conserved fertilization complex bridges sperm and egg in vertebrates
Cell (2024). AlphaFold-Multimer screening revealed a conserved sperm complex central to vertebrate fertilization.
and many more ...